1980s - The first recorded case of AIDS in South Africa was diagnosed in 1982, and although initially HIV infections seemed mainly to be occurring amongst gay men, by 1985 it was clear that other sectors of society were also affected.

1990 - The first national antenatal survey to test for HIV found that 0.8% of pregnant women were HIV-positive. It was estimated that there were between 74,000 and 120,000 people in South Africa living with HIV. Antenatal surveys have subsequently been carried out annually.

1991 - The number of diagnosed heterosexually transmitted HIV infections equalled the number transmitted through sex between men. Since this point, heterosexually acquired infections have dominated the epidemic. Several AIDS information, training and counselling centres were established.

1992 - The government's first significant response to AIDS came when Nelson Mandela addressed the newly formed National AIDS Convention of South Africa (NACOSA). The purpose of NACOSA was to begin developing a national strategy to cope with AIDS. The free National AIDS Helpline was founded.

1993 - The National Health Department reported that the number of recorded HIV infections had increased by 60% in the previous two years and the number was expected to double in 1993. The HIV prevalence rate among pregnant women was 4.3%.

1994 - The South African organisation Soul City was formed, with the aim of developing media productions to educate people about health issues, including HIV/AIDS.

1995 - The International Conference for People Living with HIV and AIDS was held in South Africa, the first time that the annual conference had been held in Africa. The then Deputy President Thabo Mbeki, acknowledged the seriousness of the epidemic, and the South African Ministry of Health announced that some 850,000 people - 2.1% of the total population - were believed to be HIV-positive.¹⁰

1996 - The HIV prevalence rate among pregnant women was 12.2%.

1997 - The HIV prevalence rate among pregnant women was 17.0%.

1998 - The pressure group Treatment Action Campaign (TAC) was founded, to campaign for the rights of people living with HIV, and to demand access to HIV treatment in South Africa for all those who were in need of it. Deputy President Thabo Mbeki launched the Partnership Against AIDS, admitting that 1,500 HIV infections were occurring every day.

1999 - The HIV prevalence rate among pregnant women was 22.4%.

2000 - The Department of Health outlined a five-year plan to combat AIDS, HIV and STIs.  A National AIDS Council was set up to oversee these developments. At the International AIDS Conference in Durban, President Thabo Mbeki made a speech that avoided reference to HIV and instead focused on the problem of poverty, fuelling suspicions that he saw poverty, rather than HIV, as the main cause of AIDS.

2001 - The HIV prevalence rate among pregnant women was 24.8%.

2002 - South Africa's High Court ordered the government to make the drug nevirapine available to pregnant women to help prevent mother to child transmission of HIV. Despite international drug companies offering free or cheap antiretroviral drugs, the Health Ministry remained hesitant about providing treatment for people living with HIV.

2003 - In November, the government finally approved a plan to make antiretroviral treatment publicly available. The HIV prevalence rate among pregnant women was 27.9%.

2004 - The South African government's treatment program began to take effect in Gauteng in March, followed shortly afterwards by other provinces.

2005 - At least one service point for AIDS-related care and treatment had been established in all of the 53 districts in the country by March, meeting the government's 2003 target. However, it was clear that the number of people receiving antiretroviral drugs was well behind initial targets. The HIV prevalence rate among pregnant women was 30.2%.

2006 – Criticism of the government's response to AIDS heightened, with UN special envoy Stephen Lewis attacking the government as 'obtuse and negligent' at the International AIDS Conference in Toronto. At the end of the year, the government announced a draft framework to tackle AIDS and pledged to improve antiretroviral drug access. Civil society groups claimed that this marked a turning point in the government's response.

Source: Avert 

Other sources :

Wikipedia